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DISQUIETUDE
Disquietude (noun) — feelings of anxiety that make you tense and irritable.
Disquietude is a valid 11-letter word worth 22 points in Scrabble (and Words With Friends letter values vary). Below are its anagrams and the shorter words hidden inside it.
Anagrams of DISQUIETUDE
No anagrams — the letters DDEEIIQSTUU only spell this word.